COMPANY PROFILEFDA ISTANDOrgan-on-Chip
Company Profile

Emulate

FDA ISTAND-Qualified Organ-on-Chip Platform

2014
Founded
$225M+
Funding
87%
DILI Sensitivity
FDA
ISTAND Qualified

COMPANY OVERVIEW

Emulate is the global leader in organ-on-chip technology, spun out of the Wyss Institute at Harvard University. In September 2024, their Liver-Chip became the first organ-chip to receive FDA ISTAND (Innovative Science and Technology Approaches for New Drugs) qualification for predicting drug-induced liver injury (DILI).

PRODUCTS

LIVER-CHIP
DILI Prediction

FDA ISTAND qualified. 87% sensitivity, 100% specificity for hepatotoxicity.

LUNG-CHIP
Respiratory

Alveolus-chip for respiratory disease and inhalation toxicology.

INTESTINE-CHIP
Gut Barrier

Intestinal absorption and gut-liver axis studies.

BRAIN-CHIP
BBB Model

Blood-brain barrier chip for CNS drug delivery.

KEY MILESTONES

  • 2014 - Spun out of Wyss Institute at Harvard
  • 2017 - First commercial Organ-Chip launch
  • 2022 - FDA Modernization Act passes, enabling non-animal testing
  • 2024 - FDA ISTAND qualification for Liver-Chip (September)
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