Multi-Organ Toxicity Assessment
Hepatotoxicity (DILI)
Drug-induced liver injury assessment with zonated hepatocyte models, bile duct cells, and immune components. Detect idiosyncratic and intrinsic hepatotoxicity.
Cardiotoxicity
Cardiac safety with contractility, electrophysiology, and hERG channel assessments. Detect QT prolongation and structural cardiotoxicity.
Nephrotoxicity
Kidney safety with proximal tubule and glomerular models. Detect drug accumulation, transport inhibition, and cellular damage.
Neurotoxicity
CNS safety with neuronal and glial models. Detect seizure liability, neurodegeneration markers, and BBB disruption.
Why Human-Relevant Toxicology?
Animal models fail to predict 70% of human toxicity. Species differences in metabolism, transporters, and target expression lead to false positives (killing good drugs) and false negatives (missing toxic drugs). Human-relevant models solve this fundamental problem.